TV Guide Releases Their Greatest Cartoons of All-Time, Here’s the Top 5

Homer, Marge, Bart, Lisa, Maggie and their kooky cast of friends and family have balanced cheeky humor and some quick-witted social satire for over 500 episodes. That only makes it TV's longest running scripted primetime series.

This prehistoric comedy from animation giants William Hanna and Joseph Barbera proved that cartoons could succeed in primetime. The exploits of the Flintsones and Rubbles shockingly only ran for six seasons but inspired a bunch of spin-offs, remakes and specials -- even a couple of live-action movies.

Bugs Bunny, Daffy Duck and company actually started at the movies back in the 1930s. The incarnation of the Looney Tunes has endured since with a unique slapstick kind of humor. Add in some Tweety, Sylvester, Porky Pig, Road Runner and Wile E. Coyote, and it'll be a long time before we say, "That's All Folks!"

A spawn of Charles M. Schulz's endearing comic strip, Charlie Brown and the Peanuts gang have been going strong for many years. A big part of their success has been the beloved holiday specials like A Charlie Brown Christmas and It's the Great Pumpkin, Charlie Brown.

Zoinks! Who would've guessed that a group of meddling kids and their always hungry dog would still be captivating audiences young and old. Beginning with the original Scooby-Doo, Where Are You! adventures and morphing into multiple series and movies, the Mystery Machine's wheels looks to be rolling for a long time to come.